Scientists have made a startling discovery - a new bat virus that shares alarming similarities with SARS-CoV-2, the culprit behind COVID-19. The researchers, based in Japan and Brazil, analyzed gut tissue samples from over 70 bats in three Brazilian sites between May and August 2019 and found the new virus, dubbed BRZ batCoV, in a Parnellβs mustached bat.
Genetic analysis reveals that BRZ batCoV is distinct enough to represent a previously unknown subgenus of betacoronavirus, but its spike protein shares an identical feature with SARS-CoV-2: a functional furin cleavage site (FCS). This feature allows the virus to infect human cells. What's even more concerning is that other bat betacoronaviruses have been found to possess this same FCS, suggesting it could easily emerge in these viruses.
While the discovery has sparked alarm, the researchers caution that their study hasn't been peer-reviewed yet and direct examination of BRZ batCoV's infectivity remains limited. Nonetheless, the findings serve as an early warning signal about the potential for a new pandemic.
The high diversity of viruses in bats makes them a key group for zoonotic disease surveillance, according to the authors. This highlights the urgent need for better tracking and monitoring of bat coronaviruses, particularly in regions like Brazil where surveillance is currently lacking.
With over five years since the emergence of COVID-19, scientists are increasingly concerned about coronaviruses causing the next big pandemic. The discovery of BRZ batCoV underscores this fear, suggesting that there may be many native bat coronaviruses with the potential to cause new epidemics in humans.
				
			Genetic analysis reveals that BRZ batCoV is distinct enough to represent a previously unknown subgenus of betacoronavirus, but its spike protein shares an identical feature with SARS-CoV-2: a functional furin cleavage site (FCS). This feature allows the virus to infect human cells. What's even more concerning is that other bat betacoronaviruses have been found to possess this same FCS, suggesting it could easily emerge in these viruses.
While the discovery has sparked alarm, the researchers caution that their study hasn't been peer-reviewed yet and direct examination of BRZ batCoV's infectivity remains limited. Nonetheless, the findings serve as an early warning signal about the potential for a new pandemic.
The high diversity of viruses in bats makes them a key group for zoonotic disease surveillance, according to the authors. This highlights the urgent need for better tracking and monitoring of bat coronaviruses, particularly in regions like Brazil where surveillance is currently lacking.
With over five years since the emergence of COVID-19, scientists are increasingly concerned about coronaviruses causing the next big pandemic. The discovery of BRZ batCoV underscores this fear, suggesting that there may be many native bat coronaviruses with the potential to cause new epidemics in humans.