Lithium Levels Linked to Autism Diagnosis Risk, But Experts Say More Research Needed
A new study published in the journal JAMA Pediatrics has found a moderate increase in the risk of autism spectrum disorder (ASD) among children born to pregnant women who were exposed to higher levels of lithium in their tap water. The research, which involved analyzing data from Denmark, suggests that as lithium levels in drinking water increased, so did the risk of ASD diagnosis.
According to the study, mothers who drank water with higher levels of lithium during pregnancy had a 24% to 26% higher risk of having a child diagnosed with ASD, compared to those whose exposure was lower. The group with the highest exposure level showed a 46% increased risk of ASD diagnosis.
However, experts caution that this association does not necessarily mean that lithium exposure directly causes autism. "The research can't show that lithium exposure leads directly to an autism diagnosis," said Dr. Beate Ritz, co-author of the study and professor of neurology at UCLA.
Ritz emphasized that further study is needed to confirm these findings and understand any potential mechanisms by which lithium may be contributing to the risk of ASD. "Any drinking water contaminants that may affect the developing human brain deserve intense scrutiny," she said in a news release.
While this association is intriguing, it's essential to note that previous studies on the effects of lithium on pregnant people with mental health disorders have not shown a link between lithium exposure and autism spectrum disorder. These studies looked at individuals exposed to much higher levels of lithium than are typically found in drinking water.
Other research has suggested connections between ASD and environmental exposures to pesticides, air pollution, and phthalates. However, these findings are not conclusive, and the exact causes of autism remain unclear.
The implications of this study's findings for public health policy are complex. Lithium levels in water, at concentrations associated with a potential increased risk of ASD, have also been linked to lower rates of hospitalization for psychiatric disorders and suicide.
As Dr. Max Wiznitzer, director of the Rainbow Autism Center, noted, "It's an interesting association, but causation is definitely not proven." He emphasized that more research is needed to understand any potential links between environmental exposures and ASD.
Ultimately, navigating the complex relationship between environmental factors and autism will require continued study and caution. As Wiznitzer said, "We have to figure out how to basically safely navigate them, and this is probably not one that's high on our list."
A new study published in the journal JAMA Pediatrics has found a moderate increase in the risk of autism spectrum disorder (ASD) among children born to pregnant women who were exposed to higher levels of lithium in their tap water. The research, which involved analyzing data from Denmark, suggests that as lithium levels in drinking water increased, so did the risk of ASD diagnosis.
According to the study, mothers who drank water with higher levels of lithium during pregnancy had a 24% to 26% higher risk of having a child diagnosed with ASD, compared to those whose exposure was lower. The group with the highest exposure level showed a 46% increased risk of ASD diagnosis.
However, experts caution that this association does not necessarily mean that lithium exposure directly causes autism. "The research can't show that lithium exposure leads directly to an autism diagnosis," said Dr. Beate Ritz, co-author of the study and professor of neurology at UCLA.
Ritz emphasized that further study is needed to confirm these findings and understand any potential mechanisms by which lithium may be contributing to the risk of ASD. "Any drinking water contaminants that may affect the developing human brain deserve intense scrutiny," she said in a news release.
While this association is intriguing, it's essential to note that previous studies on the effects of lithium on pregnant people with mental health disorders have not shown a link between lithium exposure and autism spectrum disorder. These studies looked at individuals exposed to much higher levels of lithium than are typically found in drinking water.
Other research has suggested connections between ASD and environmental exposures to pesticides, air pollution, and phthalates. However, these findings are not conclusive, and the exact causes of autism remain unclear.
The implications of this study's findings for public health policy are complex. Lithium levels in water, at concentrations associated with a potential increased risk of ASD, have also been linked to lower rates of hospitalization for psychiatric disorders and suicide.
As Dr. Max Wiznitzer, director of the Rainbow Autism Center, noted, "It's an interesting association, but causation is definitely not proven." He emphasized that more research is needed to understand any potential links between environmental exposures and ASD.
Ultimately, navigating the complex relationship between environmental factors and autism will require continued study and caution. As Wiznitzer said, "We have to figure out how to basically safely navigate them, and this is probably not one that's high on our list."